Highlights
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Senescent cells are involved in the manifestation of many age-related diseases.
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There are diverse mechanisms of senescent cells formation.
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Biomarkers considering their distinct characteristics enable efficient detection.
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Targeting senescent cells shows potential as a future therapeutic intervention.
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Senolytics and senomorphics comprise main approaches of targeting senescent cells.
https://www.sciencedirect.com/science/article/pii/S156816372030386X