Brand new paper: https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00475-0
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Sirolimus cuts down the amount of HIV in cells for those on HIV meds.
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This HIV reduction sticks around for at least 3 months after stopping the drug.
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It slows down the activity of certain immune cells and reduces a marker of exhaustion on others.
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Doesn’t change how the immune system targets HIV or the active virus levels.
There is a also study in China using rapamycin to reduce Hepatitis B viral load.