Always curious about curve response. What kind of curve for rapamycin is?
What curve responses of other commonly taken drugs like metformin, telmisartan?
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Linear: Direct proportionality between exposure/treatment and effect.
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Sigmoid: Effects start slow, increase sharply, then level off.
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Bell/Inverted U-shaped: Optimal effect at moderate levels, less effective at extremes.
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U-shaped: Low and high levels might have similar effects, different at intermediate.
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J-shaped: Effect minimal at first, then increases significantly post a threshold.
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L-shaped: Sharp decline with minimal recovery.
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Threshold: No effect until a critical point, then significant change.
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Exponential: Rapid effects increase/decrease post-exposure.
U and J shapes often indicate complex drug responses or health outcomes where moderate levels might be optimal or where effects differ dramatically at different exposure levels.