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“The greatest risk reduction was observed in participants consuming at least 2 of the following per day: 5 servings of tea, 1 serving of red wine, and 0.5 servings of berries, compared with those who did not achieve any of these intakes (AHR, 0.62; 95% CI, 0.46-0.84).”
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Speculation but the benefit curve would have to be an inverted U. At high doses, flavonoids could act as mutagens, pro-oxidants generating free radicals, and as inhibitors of enzymes involved in hormone metabolism.