Peptides / Bioregulators

It was shown that long-term treatment with some peptide preparations increased mean life span by 20-40%, slow down the age-related changes in the biomarkers of aging and suppressed development of spontaneous and induced by chemical or radiation carcinogens tumorigenesis in rodents

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PEPTIDE FREQUENTLY ASKED QUESTIONS

Disclaimer: Please note that only your own physician can determine your precise needs, but in order to give you some information these answers are based upon the ‘average person’ and clinical/ published results.

What is a peptide bioregulator?
A peptide is a short chain of amino acids, identified by the fact that it is shorter than a protein, and so can be absorbed easily via the digestive system. Each organ or bodily function has its own unique peptide bioregulator.
Peptide bioregulators have been shown to shortcut the protein synthesis process by interacting directly with cell DNA – meaning that organs can build and repair tissues easier and quicker when peptide bioregulators are active.

What combination of peptides would be best to consider for the elderly in general?
Glandokort® - adrenal peptide, Vladonix® -thymus peptide and Ventfort® - blood vessels peptide.

Would there be a difference between dosing for men and women?
Not particularly, the dosing is more related to need than sex or body weight

Is it best to include the blood vessel peptide in all combinations used?
Yes it is recommended, the blood vessel peptide is known as Ventfort®

What is the typical dosing regimen for the peptides in general?
Two capsules a day for 10-days - a total of 20 capsules equivalent to one pack - for general support this can be repeated again in 6-months’ time, if the need is greater then it can be repeated again in 2 to 3 months’ time, if the need is felt to be great then typically the regimen is repeated every month.

How many peptide complexes can I take at the same time?
You can combine up to 5 peptide complexes at the same time.

What are the side effects?
15 million people have undergone the peptide treatment for 30 years and no side effects have been found. The fact is that peptides in animals and humans are identical and our body sees them as its own. Peptides only normalize the protein synthesis and they are not able to overstimulate it.

Are there any contraindications?
Individual intolerance to the components, pregnancy and breastfeeding.

Can I take peptides with other supplements too?
Yes, you can.

How can I be sure that peptides have an actual effect on me?
Sometimes it can be hard to notice changes subjectively, so an objective method can be helpful. Ask your doctor what tests could be done to assess your current health condition. Do them before and after taking appropriate peptides

Why aren’t there any similar peptide complexes from other companies?
First of all, the process of extracting peptides is patented. Secondly, Russian scientists started working on this class of medical substances 40 years ago at the request of the military, therefore they had access to all necessary funds. There were a 30-year study on rats, a study on apes and clinical trials. Nowadays just a few researches can be funded so well to be conducted on the same large scale.

Can Endoluten be consumed alongside any other supplements?
As they are each tailored to a specific gene, there is no problem with consuming multiple supplements at one time.

Can Endoluten be used to regulate sleep?
As it promotes melatonin secretion, Endoluten could be used to encourage a regular sleep pattern

Are there any known side effects for using this supplement?
Ventfort has been tested for many years on thousands of individuals, without reports of any serious side effects.

What combination of peptides should i take?
According to Prof. Vladimir Khavinson, the president of European Association of Gerontology and Geriatrics, the first class combination consists of Endoluten (Neuro-endocrine system), Vladonix (Immune system), Cerluten (Brain), Sigumir (Joints and Bones), Svetinorm (Liver) and Ventfort (Blood vessels) for one or two months twice a year. Endoluten and Vladonix are the two most important geroprotector that are able to extend life by 30-40%.

Here are some general recommendations:

Natural Peptides Combinations

  • Digestive system: A-7 Svetinorm A-1 Suprefort A-10 Stamakort
  • Cardiovascular system: A-3 Ventfort A-14 Chelochart A-6 Vladonix
  • Central nervous system: A-5 Cerluten A-3 Ventfort A-7 Svetinorm
  • Immune system: A-8 Endoluten A-6 Vladonix® A-3 Ventfort
  • Locomotor apparatus: A-4 Sigumir A-3 Ventfort A-6 Vladonix A-21 Bonothyrk
  • Carbohydrate metabolism disorders: A-1 Suprefort A-3 Ventfort
  • Lipoprotein metabolism disorders: A-7 Svetinorm A-1 Suprefort A-3 Ventfort
  • Thyroid gland: A-2 Thyreogen A-3 Ventfort
  • Adverse factors (chemotherapy, long-term ionizing irradiation): A-6 Vladonix A-7 Svetinorm A-8 Endoluten A-20 Bonomarlot
  • Adverse factors (professional or psychoemotional stress): A-6 Vladonix A-8 Endoluten A-17 Glandokort
  • Visual organ: A-11 Visoluten A-5 Cerluten A-3 Ventfort
  • Urinary excretory system: A-6 Vladonix A-12 Chitomur A-9 Pielotax
  • Male reproductive system: A-13 Testoluten A-16 Libidon A-17 Glandokort
  • Female reproductive system: A-15 Zhenoluten A-2 Thyreogen A-3 Ventfort
  • Respiratory system: A-6 Vladonix A-19 Taxorest A-3 Ventfort
  • Intensive physical activity: A-6 Vladonix A-4 Sigumir A-3 Ventfort A-18 Gotratix A-5

@ksbradley

According to this paper in PubMed, BPC 157 may be a good hangover cure, at least for rats.

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BPC-157 injected sub-q noticably reduces post-workout pain and improves my digestion within a few days.

MOTS-C improves my cardio performance, allowing me to run faster and longer on the treadmill during HIIT.

SS-31 improved my kidney function (posted data elsewhere).

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Remarkable, @AgentSmith. As much as I would like to run farther and faster, improving my workout gains would be subsidiary to its positive effects on kidney function. Even more beneficially, at least for me right now, the above paper found that BPC 157 can heal a compressed spine. The spine was intentionally damaged for the sake of the experiment.

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I probably have a damaged spine from too much heavy lifting. I will say that a few days on BPC eliminated chronic lower back pain, but that was muscle related.

TB500 is another favorite for healing, but I have not used it myself yet.

Unfortunately, the MOTS-C effect wears off quickly. I can run ~0.5mph faster, but only for a day or so. It is fun but probably meaningless. I am now planning on taking it on my rapamycin days, though, since it increases mTORC2 activity.

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@ksbradley, 5-mg injections seems like a lot. I’ve read that doses a tenth of that yield positive results.

Maybe so. 5mg every few days is a common dose.

Tim - I definitely dont do 5MG injection all at once.
My vial contains 5mg and I reconstitute it. A bottle typically gets me about 8ish injections

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@AgentSmith and @ksbradley, thanks.

Have either of you ever bought anything from or heard anything about Sterile Solutions?

Not familiar with them

This is fascinating & new to me. Thanks for the information you’ve posted. Do you have any knowledge to share on dosing/cycles for Tesamorelin, Ipamorelin, CJC-1295? Is this something you do a few times a year or more regularly? (Wondering how it fits in with rapa too)
(I see your FAQ above is that for tablet form though?)

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The FAQ is for Peptide Bioregulators which is completely different from Peptides
Peptide bioregulators are signal agents that basically tell your body to begin healing specific organs.
These are used as pill form [almost all the time anyways]
Peptides are injections usually.
There are lots of videos and dosage calculators out there.
Dr Peter Attia and Jason Campbell are probably the two best for some initial guidance

Dosage can vary. I would do research and always start on the lower end to see how your body reacts.
Just make sure to reconstitute properly and then calculate based on how much Bacteriostatic water is used.

For Ipamorelin for example: Most research subjects are given an ipamorelin dose of 200-300 mcg per day, for 8-12 weeks, followed by a 4 week washout period.

Here is a great online calculator ince you have reconstituted:

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Research-Peptides-the-Ultimate-Guide-Final-1-1-3-compressed.pdf (1.8 MB)

This is just another thorough free guide for you all on Peptides

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Thanks for the resources! Looking at the options for composition & muscle gain…Does ipamorelin increase or decrease appetite, or no effect on it? The PDF maybe suggests it does increase appetite but I could be reading it wrong.

I’ve been looking at pricing, unless I’m misunderstanding it - it’s quite pricey. If you could only afford one peptide is it still worthwhile? Or does the power come from stacking.

I dont buy from that site, just sharing that site for relevant info.
I order from other places.
Its not that pricey at all.

Ipamorelin and Tesamorelin and CJC-1295 are three similar acting peptides that are sometimes stacked but dont need to be.
For muscle composition Ipamorelin would be my one for sure.
It does effect grehlin but not in a big way. I didnt notice anything personally for hunger…

Ok, thank you. Price wise, Tesamorelin seems one of the more expensive ones here. £24 for 2mg, Daily dose: 1mg (1000mcg) = 2 shots in one vial. Maybe it’s more affordable where you are. I’ll look into the others!

Peptides currently in my program (since July 2023)
Morning - 500ug BPC-157 + 500ug TB500
Night 20 nights a month - 250ug CJC-1295 noDAC + 400ug Ipamorelin
Weekly - Terzepatide

Will be adding a few more in a month or so.
MOTs-C, Epithalon and have my eye on a couple more.

FOX04-DRI is on my list but so expensive at the proper dose, even from my current manufacturers.

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Love the protocol Steve.

I am on ipamorelin and Tesamorelin
Use BPC-157 only when need recovery
Just started a vial of GHRP-2 to mix in. Was taking CJC-1295 but taking a break while trying other peptides
Definitely want to take Epitalon for longevity

Also considering hgh Frag 176-191 which is the same as AOD9604 to help me get cut and ripped for rhe summer.
I am 53 but proud to still have a six pack and beach ready even though I enjoy a beer or two 4-5 nights a week.

If an injury happens I may order some TB500 to have on hand as well.

Also did cycles of bioregulators for brain, heart, circulation, lungs, prostate and thyroid.
Will do a cycle of each bioregulator once every six months.

Open to hearing anyone elses benefits, trials, placeboe effect, side effects etc.

Keep the post alive

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